REPRODUCTIVE-ENHANCING POTENTIAL OF METHANOL EXTRACT OF SPHENOSTYLIS STENOCARPA SEED ON MALE WISTAR RATS


A study was undertaken on the reproductive-enhancing potential of Sphenostylis stenocarpa seed methanol extract on male Wistar rats. A total of 144 adult male rats were used for the experiment, divided into four groups (A – D), and replicated thrice. Group A served as the standard control, while Groups B, C, and D received three graded doses (800 mg/kg, 1200 mg/kg, and 1600 mg/kg) of the extract by oral intubation. The rats' gonad characteristics, sperm parameters, and hormonal analyses were determined weekly using standard procedures from Week 0 (day 1) to Week 12. Data obtained were analyzed using analysis of variance (ANOVA). Means with differences in pvalues (< 0.05) were considered significant. The results showed overall dose and significant timedependent differences in the mean weekly gonad characteristics of the male rats in the treatment groups compared to the control. The body weights of the male rats significantly reduced (p < 0.05), whereas the testes wei


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